• November 1, 2009 at 3:34 pm

    I don’t get to post in here too much..as my wife is in late stage Early Onset Alzheimer’s and is 65 years of age. I’ve been caring for her at home..and she is presently under hospice care.

    The reason for my writing is that in August of 09, and again in October of 09…..my wife suffered two incidents seizures. In august of 09, she had what is called a “gran mal” type of seizure, which is similar to seizures related to Epilepsy. She had the first seizure around 6:30 PM and the second around 8:30 PM. She was seizure free until October of 09….first seizure was around 9:30 AM and the second around 11:30.

    I did some research and this is what I came up with

    Seizures in Alzheimer’s disease: clinicopathologic study.

    Mendez MF, Catanzaro P, Doss RC, ARguello R, Frey WH 2nd.

    Department of Neurology, St. Paul-Ramsey Medical Center, Minnesota.

    New-onset epileptic seizures occur in patients with Alzheimer’s disease (AD), but the nature and underlying reasons for these seizures are unclear. We identified new-onset, nonsymptomatic seizures in 77 (17%) of 446 patients with uncomplicated, definite AD on autopsy. Among these seizure patients, 69 had generalized tonic-clonic seizures, and 55 had less than three total seizures. The seizure patients had a younger age of dementia onset than did the remaining AD patients; however, at seizure onset, they averaged 6.8 years into their AD and had advanced dementia. When further compared to 77 AD controls, matched for age of onset and duration, the seizure patients did not differ on medical illnesses, amount of medications, and degree of focal neuropathology. We conclude that a few unprovoked generalized seizures frequently occur late in the course of AD, and that AD patients with a younger age of dementia onset are particularly susceptible to seizures.

  • November 5, 2009 at 1:21 pm

    Thanks for sharing that information Watchman….and I’m so sorry to hear that Mary has gone downhill so badly.

    My thoughts and prayers and with you both.